期刊論文 / Journal Article

 * Corresponding author

 

2023

1. Weerawatanakorn, M., He, S., Chang, CH., Koh, YC., Yang, MJ., Pan, MH*. High Gamma-Aminobutyric Acid (GABA) Oolong Tea Alleviates High-Fat Diet-Induced Metabolic Disorders in Mice. ACS Omega. 2023, doi.org/10.1021/acsomega.3c04874.

2. How, CM., Cheng, KC., Li, YS., Pan, MH*., Wei, CC*. Tangeretin Supplementation Mitigates the Aging Toxicity Induced by Dietary Benzo [a] pyrene Exposure with Aberrant Proteostasis and Heat Shock Responses in Caenorhabditis elegans. Journal of Agricultural and Food Chemistry. 2023, doi.org/10.1021/acs.jafc.3c02307.

3. Lin, WS., Cheng, WC., Ho, PY., Ho, CT., Pan, MH*. Regulation of Xenobiotic-Metabolizing Enzymes by 5-Demethylnobiletin and Nobiletin to Mitigate Benzo [a] pyrene-Induced DNA Damage In Vitro and In Vivo. Journal of Agricultural and Food Chemistry. 2023, doi.org/10.1021/acs.jafc.3c03347.

4. Koh YC., Lin SJ., Hsu KY., Nagabhushanam K., Ho CT., Pan, MH*. Pterostilbene Enhances Thermogenesis and Mitochondrial Biogenesis by Activating the SIRT1/PGC-1α/SIRT3 Pathway to Prevent Western Diet-Induced Obesity. Molecular Nutrition & Food Research. 2023; e2300370.

5. Xiao, Y., Pan, MH., Chiou, YS., Li, Z., Wei, S., Yin, X., Ding, B. Insights from β-Conglycinin and Glycinin into the Mechanism of Nanoliposome-Soybean Protein Isolate Interactions. Journal of Agricultural and Food Chemistry. 2023;71(28):10718-10728.

6. Hsu KY., Ho CT., Pan, MH*. The therapeutic potential of curcumin and its related substances in turmeric: From raw material selection to application strategies. Journal of Food and Drug Analysis. 2023;31(2):194-211.

7. Wen CJ., Koh YC., Tung YC., Ho, PY., Hsieh, SC., Lo, YC., Tsai, JS., Pan, MH*. Cross-Sectional Study: New Approach for Diagnostic Identification of Non-Robust Older Adult. Molecular Nutrition & Food Research, 2023;67(13):e2300056.

8. Chang CH, Lien YT, Lin WS, Nagabhushanam K, Ho CT, Pan, MH*. Protective Effects of Piceatannol on DNA Damage in Benzo[a]pyrene-Induced Human Colon Epithelial Cells. Journal of Agricultural and Food Chemistry. 2023;71(19):7370-7381.

9. Koh, YC., Ho, CT., Pan, MH*. The Role of Mitochondria in Phytochemically Mediated Disease Amelioration. Journal of Agricultural and Food Chemistry. 2023;71(18):6775-6788.

10. Koh YC., Chok D., Chang CH., Wei, CC., Wu, CT., Cheng, KC., Nagabhushanam, K., Ho, CT., Pan, MH*. Prevention of Glutamate-Induced Neurodegeneration by Piceatannol via Mitochondrial Rescue In Vitro and In Vivo. Molecular Nutrition & Food Research. 2023;67(13):e2300139.

11. Wongwaiwech, D., Kamchonemenukool, S., Ho, CT., Li, S., Majai, N., Rungrat, T., Sujipuli, K., Pan, MH., Weerawatanakorn, M. Bioactives from Crude Rice Bran Oils Extracted Using Green Technology. Molecules. 2023, 28(6), 2457.

12. Lin, WS., Chueh, TL., Nagabhushanam, K., Ho, CT., Pan, MH*. Piceatannol and 3′-Hydroxypterostilbene Alleviate Inflammatory Bowel Disease by Maintaining Intestinal Epithelial Integrity and Regulating Gut Microbiota in Mice. Journal of Agricultural and Food Chemistry. 2023,71(4), 1994–2005.

13. Koh, Y. C., Kuo, LH., Chang, YY., Tung, YC., Lo, YC., Pan, MH*. Modulatory Effect of Fermented Black Soybean and Adlay on Gut Microbiota Contributes to Healthy Aging. Molecular Nutrition & Food Research. 2023, 2200700.

14. Xu, T., Pan, MH., Chiou, YS., Li, Z., Wei, S., Yin, X., Ding, B. Improvement of emulsifying properties of potato starch via complexation with nanoliposomes for stabilizing Pickering emulsion. Food Hydrocolloids. 2023, 136, 108271.

15. Lin, HT., Yeh, AI., Ho, THD., Pan, MH., Chen, SH. Molecular weight, chain length distribution and long-term retrogradation of cassava starch modified by amylomaltase. Food Hydrocolloids. 2023, 134, 108027.

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2022

1. Lin, WS., Choudhary, D., Lo, YC., Pan, MH*. Pharmacological bioactivity of enzymatically bio-transformed ginsenosides. Journal of Food Bioactives. 2022, 20.

2. Chen, YT., Lin, YY., Pan, MH., Ho, CT., Hung, WL. Inhibitory effects of rooibos (Aspalathus linearis) against reactive carbonyl species and advanced glycation end product formation in a glucose-bovine serum albumin model and cookies. Food Chemistry: 2022, X, 16, 100515.

3. Koh, YC., Tsai, YW., Lee, PS., Nagabhushanam, K., Ho, CT., Pan, MH*. Amination potentially augments the ameliorative effect of curcumin on inhibition of the IL-6/Stat3/c-Myc pathway and gut microbial modulation in colitis-associated tumorigenesis. Journal of Agricultural and Food Chemistry. 2022. 70(46), 14744-14754.

4. Kamchonemenukool, S., Ho, CT., Boonnoun, P., Li, S., Pan, MH., Klangpetch, W., & Weerawatanakorn, M. High Levels of Policosanols and Phytosterols from Sugar Mill Waste by Subcritical Liquefied Dimethyl Ether. Foods. 2022, 11(19), 2937.

5. Lin, HT., Yeh, AI., Ho, THD., Pan, MH., & Chen, SH. Molecular weight, chain length distribution and long-term retrogradation of cassava starch modified by amylomaltase. Food Hydrocolloids. 2023, 134, 108027.

6. Wei, CC., Li, SW., Wu, CT., How, CM., & Pan, MH*. Dietary Methylglyoxal Exposure Induces Alzheimer’s Disease by Promoting Amyloid β Accumulation and Disrupting Autophagy in Caenorhabditis elegans. Journal of Agricultural and Food Chemistry. 2022, 70(32), 10011-10021.

7. Lin, WS., Lai, YJ., Nagabhushanam, K., Ho, CT., Pan, MH*. S‐Allylcysteine Potently Protects against PhIP‐Induced DNA Damage via Nrf2/AhR Signaling Pathway Modulation in Normal Human Colonic Mucosal Epithelial Cells. Molecular Nutrition & Food Research. 2022, 66(16), 2101141.

8. Koh, YC., Lin, SJ., Nagabhushanam, K., Ho, CT., Pan, MH*. The Anti‐Obesity and Anti‐Inflammatory Capabilities of Pterostilbene and its Colonic Metabolite Pinostilbene Protect against Tight Junction Disruption from Western Diet Feeding. Molecular Nutrition & Food Research. 2022, 66(16), 2200146.

9. Chiou, YS., Lan, YM., Lee, PS., Lin, Q., Nagabhushanam, K., Ho, CT., Pan, MH*. Piceatannol prevents colon cancer progression via dual‐targeting to M2‐polarized tumor‐associated macrophages and the TGF‐β1 positive feedback signaling pathway. Molecular Nutrition & Food Research. 2022, 2200248.

10. Pung, HC., Lin, WS., Lo, YC., Hsu, CC., Pan, MH*. Ulva prolifera polysaccharide exerts anti-obesity effects via upregulation of adiponectin expression and gut microbiota modulation in high-fat diet-fed C57BL/6 mice. Journal of Food and Drug Analysis. 2022, 30(1), 46-61.

11. Wang, Q., Pan, MH., Chiou, Y. S., Li, Z., Ding, B. Surface characteristics and emulsifying properties of whey protein/nanoliposome complexes. Food Chemistry. 2022, 384, 132510.

12. Tung, YC., Liang, ZR., Yang, MJ., Ho, CT., Pan, MH*. Oolong tea extract alleviates weight gain in high-fat diet-induced obese rats by regulating lipid metabolism and modulating gut microbiota. Food & Function. 2022, 13(5), 2846-2856.

13. Chen, PH, Chang, CH, Lin, WS, Nagabhushanam, K, Ho, CT, Pan, MH*. S-allylcysteine Ameliorates Aging Features Via Regulating Mitochondrial Dynamics in Naturally Aged C57BL/6J Mice. Molecular nutrition & food research. 2022, e2101077.

14. Wang, Q., Pan, MH., Chiou, YS., Li, Z., Wei, S., Yin, X., Ding, B. Mechanistic understanding of the effects of ovalbumin-nanoliposome interactions on ovalbumin emulsifying properties. LWT. 2022, 157, 113067.

15. Lee, PS., Lu, YY., Nagabhushanam, K., Ho, CT., Mei, HC., Pan, MH*. Calebin-A prevents HFD-induced obesity in mice by promoting thermogenesis and modulating gut microbiota. Journal of Traditional and Complementary Medicine. 2022

16. Wang, Q., Pan, MH., Chiou, YS., Li, Z., Wei, S., Yin, X., Ding, B. Insights from alpha-Lactoalbumin and beta-Lactoglobulin into mechanisms of nanoliposome-whey protein interactions. Food Hydrocolloids, 2022. 125, 107436.

2021

1. Hung, WL, Hsiao, YT, Chiou, YS, Nagabhushanam, K, Ho, CT, Pan, MH*. Hepatoprotective effect of piceatannol against carbon tetrachloride-induced liver fibrosis in mice. Food & Function. 2021. 12: 11229-11240.

2. Chen, RJ, Lyu, YJ, Chen, YY, Lee, YC, Pan, MH, Ho, YS, Wang, YJ. Chloroquine potentiates the anticancer effect of pterostilbene on pancreatic cancer by inhibiting autophagy and downregulating the RAGE/STAT3 pathway. Molecules. 2021. 26: 6741

3. Koh, YC, Lee, PS, Kuo, YL, Nagabhushanam, K, Ho, CT, Pan, MH*. Dietary pterostilbene and resveratrol modulate the gut microbiota influenced by circadian rhythm dysregulation. Molecular Nutrition & Food Research. 2021. 65: 2100434.

4. Lin, TN, Lin, WS, Chou, YC, Nagabhushanam, K, Ho, CT, Pan, MH*. Oxyresveratrol inhibits human colon cancer cell migration through regulating epithelial–mesenchymal transition and microRNA. Food & Function. 2021, 12(20), 9658-9668.

5. Koh, YC, Ho, CT, Pan, MH*. Recent advances in health benefits of stilbenoids. Journal of Agricultural and Food Chemistry. 69: 10036-10057.

6. Chou, YT, Koh, YC, Nagabhushanam, K, Ho, CT, Pan, MH*. A natural degradant of curcumin, feruloylacetone inhibits cell proliferation via inducing cell cycle arrest and a mitochondrial apoptotic pathway in HCT116 colon cancer cells. Molecules. 2021. 26: 4884.

7. Lee, PS. Nagabhushanam, K, Ho, CT, Pan, MH*. Inhibitory effect of garcinol on obesity-exacerbated colitis, mediated colon carcinogenesis. Molecular Nutrition and Food Research. 2021. 10: e2100410. 

8. Chou, YC, Lin, YS, Lin, PS, Tung, YC, Ho, CT, Pan, MH*. Dietary 5-demethylnobiletin modulates xenobiotic-metabolizing enzymes and ameliorates colon carcinogenesis in benzo[a]pyrene-induced mice. Food and Chemical Toxicology. 2021. 155: 112380.

9. Fan-Jiang, PY, Lee, PS, Nagbhushanam, K, Ho, CT, Pan, MH*. Pterostilbene attenuates high-fat diet and dextran sulfate sodium-induced colitis via suppressing inflammation and intestinal fibrosis in mice. Journal of Agricultural and Food Chemistry. 2021. 69: 7093-7103.

10. Chang, ML, Lin, YT, Kung, HN, Hou, YC, Liu, JJ, Pan, MH, Chen, HL, Yu, CH, Tsai, PJ. A triterpenoid-enriched extract of bitter melon leaves alleviates hepatic fibrosis by inhibiting inflammatory responses in carbon tetrachloride-treated mice. Food & Function. 2021. Doi: 10.1039/d1fo00884f

11. Chen, Y, Yi, XZ, Pan, MH, Chiou, YS, Li, ZS, Wei, SD, Yin, XL, Ding, BM. The interaction mechanism between liposome and whey protein: Effect of liposomal vesicles concentration. Journal Of Food Science. 2021. 86: 2491-2498.

12. Chi, HL, Yeh, AI, Pan, MH, Chen, SH. Physicochemical properties and film formation of the chitin hydrocolloid fabricated by a novel green process. Journal of Applied Polymer Science. 2021. 138: e50762.

13. Hsiao, TH, Wang, YH, Lin WS, Cheng, YC, Kalyanam, N, Ho, CT, Pan, MH*. Molecular mechanisms of the anti-obesity properties of Agardhiella subulata in mice fed a high-fat diet. Journal of Agricultural and Food Chemistry. 2021. doi: 10.1021/acs.jafc.1c01117

14. Tung, YC, Shih, YA, Kalyanam, N, Ho, CT, Cheng, AC, Pan, MH*. Coleus forskohlii and Garcinia indica extracts attenuated lipid accumulation by regulating energy metabolism and modulating gut microbiota in obese mice. Food Research International. 2021. 142: 110143.

15. Chi, HL, Yeh, AI, Pan, MH, Chen, SH*. Physicochemical properties and film formation of the chitin hydrocolloid fabricated by a novel green process. Journal of Applied Polymer Science. 2021. e50762.

16. Lien, KW, Pan, MH, Ling, MP*. Levels of heavy metal cadmium in rice (Oryza sativa L.) produced in Taiwan and probabilistic risk assessment for the Taiwanese population. Environmental Science and Pollution Research. 2021. doi: 10.1007/s11356-020-11902-w.

17. Koh, YC, Liu, SY, Wu, JC, Chou, YC, Nagabhushanam, K, Ho, CT, Pan, MH*. A new metabolite: The effects of aminated tetrahydrocurcumin on inducible nitric oxide synthase and cyclooxygenase-2. Journal of Cancer Research and Practice. 2021. Doi: 10.4103/JCRP.JCRP_21_20.

18. Chen, WJ*, Tsai, JH, Hsu, LS, Lin, CL, Hong, HM, Pan, MH*. Quercetin blocks the aggressive phenotype of triple-negative breast cancer by inhibiting IGF1/IGF1R-mediated EMT program. Journal of Food & Drug Analysis. 2021, 29(1):98-112.

 

2020

1. Lee, PS, Chiou, YS, Chou, PY, Kalyanam, N, Ho, CT, Pan, MH*. 3′-Hydroxypterostilbene inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin carcinogenesis. Phytomedicine. 2020. 3(81):153432.

2. Lin, WS, Lai, YJ, Kalynam, N, Ho, CT, Pan, MH*. S‐allylcysteine Inhibits PhIP/DSS‐induced Colon Carcinogenesis Through Mitigating Inflammation, Targeting Keap1, and Modulating Microbiota Composition in Mice. Molecular Nutrition and Food Research. 2020. 64: e2000576.

3. Chou, YC, Ho, PY, Chen, WJ, Wu, SH, Pan, MH*. Lactobacillus fermentum V3 ameliorates colitis-associated tumorigenesis by modulating the gut microbiome. American Journal of Cancer Research. 2020. 10(4):1170-1181.

4. Koh, YC, Lin, YC, Lee, PS, Lu, TJ, Lin, KY, Pan, MH*. A multi-targeting strategy to ameliorate high-fat-diet- and fructose-induced (western diet-induced) non-alcoholic fatty liver disease (NAFLD) with supplementation of a mixture of legume ethanol extracts. Food & Function. 2020. 11(9): 7545-7560

5. Tung, YC, Chou, RF, Nagabhushanam, K, Ho, CT, Pan, MH*. 3'-Hydroxydaidzein Improves Obesity Through the Induced Browning of Beige Adipose and Modulation of Gut Microbiota in Mice with Obesity Induced by a High-Fat Diet. Journal of Agricultural and Food Chemistry. 2020. 68(49): 14513-14522.

6. Tung, YC, Liang, ZR, Chou, SF, Ho, CT, Kuo, YL, Cheng, KC, Lu, TJ, Chang, YC, Pan, MH*. Fermented Soy Paste Alleviates Lipid Accumulation in the Liver by Regulating the AMPK Pathway and Modulating Gut Microbiota in High-Fat-Diet-Fed Rats. Journal of Agricultural and Food Chemistry. 2020. 68(35): 9345-9357.

7. Hsiao, YH, Ho, CT, Pan, MH*. Bioavailability and health benefits of major isoflavone aglycones and their metabolites. Journal of Functional Foods. 2020. 74:104164.

8. Lien, KW, Ling, MP, Pan, MH*. Probabilistic risk assessment of patulin in imported apple juice and apple‐containing beverages in Taiwan. Journal of the Science of Food and Agriculture. 2020. 100(13):4776-4781.

9. Lai, CS, Ho, CT, Pan, MH*. The Cancer Chemopreventive and Therapeutic Potential of Tetrahydrocurcumin. Biomolecules. 2020. 10(6):831.

10. Wang, YJ, Chen, YY, Hsiao, CM, Pan, MH, Wang, BJ, Chen, YC, Ho, CT, Huang, KC, Chen, RJ. Induction of Autophagy by Pterostilbene Contributes to the Prevention of Renal Fibrosis via Attenuating NLRP3 Inflammasome Activation and Epithelial-Mesenchymal Transition. Frontiers in Cell and Developmental Biology. 2020. 8:436.

11.  Lee, PS, Chiou, YS, Nagabhushanam, K, Ho, CT, Pan, MH*. 3′-Hydroxypterostilbene Potently Alleviates Obesity Exacerbated Colitis in Mice. Journal of Agricultural and Food Chemistry. 2020.

12. Cheng, AC, Jiang, WR, Hsiao, YH, Badmaev, V, Ho, CT, Yu, RC, Pan, MH*. Promoting effect of Se-allylselenocysteine on 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin tumorigenesis. Journal of Food Bioactives, 2020. 9.

13. Lin, WS, Leland, JV, Ho, CT*, Pan, MH*. Occurrence, bioavailability, anti-inflammatory and anti-cancer effects of pterostilbene. Journal of Agricultural and Food Chemistry. 2020.

14. Chou, YC, Li, S, Ho, CT, Pan, MH*. Preparation and evaluation of self-microemulsifying delivery system containing 5-demethyltangeretin on inhibiting xenograft tumor growth in mice. International Journal of Pharmaceutics. 2020. 579:119134.

15. Koh, YC, Ho, CT, Pan, MH*. Recent advances in cancer chemoprevention with phytochemicals. Journal of Food and Drug Analysis. 2020. 28(1):14-37.

​​

​​2019

1. Pan, MH*, Koh, YC, Lee, TL, Wang, B, Chen, WK, Nagabhushanam, K, Ho, CT. Resveratrol and Oxyresveratrol Activate Thermogenesis via Different Transcriptional Coactivators in High-Fat Diet-Induced Obese Mice. Journal of Agricultural and Food Chemistry. 2019. 67(49):13605-13616

2. Lin, ZH, Chan, FY, Pan, MH, Tung, YC, Su, ZY. Aged Citrus Peel (Chenpi) Prevents Acetaminophen-Induced Hepatotoxicity by Epigenetically Regulating Nrf2 Pathway. The American Journal of Chinese Medicine. 2019. 47 (8):1833-1851.

3. Thang, SK., Chen, PY., Gao, WY., Wu, MJ., Pan, MH., Yen, JH. Xanthohumol Suppresses NPC1L1 Gene Expression through Downregulation of HNF-4α and Inhibits Cholesterol Uptake in Caco-2 Cells. Journal of Agricultural and Food Chemistry. 2019. 67(40):11119-11128.

4. Lee, PS., Teng, CY., Hsieh, KF., Chiou, YS., Wu, JC., Lu, TJ., Pan, MH*. Adzuki Bean Water Extract Attenuates Obesity by Modulating M2/M1 Macrophage Polarization and Gut Microbiota Composition. Molecular Nutrition and Food Research. 2019. 63(23): e1900626.

5. Tian, X., Guo, S., Zhang, S., Lee, PS., Wang, T., Ho, CT., Pan, MH., Bai, N. Chemical characterization of main bioactive constituents in Paeonia ostii seed meal and GC‐MS analysis of seed oil. Journal of Food Biochemistry. 2019. e13088.

6. Pan, MH*, Li, MY., Tsai, ML., Pan, CY., Badmaev, V., Ho, CT., and Lai, CS*. A mixture of citrus polymethoxyflavones, green tea polyphenols and Lychee extracts attenuates adipogenesis in 3T3-L1 adipocytes and obesity-induced adipose inflammation in mice. Food & Function. 2019. DOI: 10.1039/C9FO02235J.

7. Hung, WL., Ho, CT., Pan, MH*. Targeting the NLRP3 inflammasome in Neuroinflammation: Health Promoting Effects of Dietary Phytochemicals in Neurological Disorders. Molecular Nutrition and Food Research. 2019. 64(4):e1900550.

8. Oh, WY., Chiou, YS., Lee, PS., Pan, MH., Shahidi, F. Lipophilised resveratrol affects the generation of reactive nitrogen species in murine macrophages and cell viability of human cancer cell lines. Journal of Food Bioactives. 2019. 7:73–77.

9. Koh, YC., Li, S., Chen, PY., Wu, JC., Kalyanam, N., Ho, CT., Pan, MH*. Prevention of Vascular Inflammation by Pterostilbene via Trimethylamine‐N‐Oxide Reduction and Mechanism of Microbiota Regulation. Molecular Nutrition and Food Research. 2019. e1900514.

10. Chen, PY., Li, S., Koh, YC., Wu, JC., Yang, MJ., Ho, CT., Pan, MH*. Oolong Tea Extract and Citrus Peel Polymethoxyflavones Reduce Transformation of l-Carnitine to Trimethylamine-N-Oxide and Decrease Vascular Inflammation in l-Carnitine Feeding Mice. Journal of Agricultural and Food Chemistry. 2019. 67(28):7869-7879.

11. Yang, G., Lin, CC., Yang, Y., Yuan, L., Wang, P., Wen, X., Pan, MH*., Zhao, H., Ho, CT., Li, S. Nobiletin Prevents Trimethylamine Oxide-Induced Vascular Inflammation via Inhibition of the NF-κB/MAPK Pathways. Journal of Agricultural and Food Chemistry. 2019. 67(22):6169-6176.

12. Hsiao, YH., Chen, NC., Koh, YC., Nagabhushanam, K., Ho, CT., Pan, MH*. Pterostilbene Inhibits Adipocyte Conditioned-Medium-Induced Colorectal Cancer Cell Migration through Targeting FABP5-Related Signaling Pathway. Journal of Agricultural and Food Chemistry. 2019. 10.1021/acs.jafc.9b03997.

13. Lin, JN., Lee, PS., Mei, NW., Cheng, AC., Yu, RC., Pan, MH*. Effects of Ginseng Dietary Supplementation on a High-Fat Diet-induced obesity in C57BL/6 Mice. Food Science and Human Wellness. 2019. https://doi.org/10.1016/j.fshw.2019.03.003.

14. Tung, YC., Chou, YC., Hung, WL., Cheng, AC., Yu, RC., Ho, CT., Pan, MH*. Polymethoxyflavones: Chemistry and Molecular Mechanisms for Cancer Prevention and Treatment. Current Pharmacology Reports. 2019. https://doi.org/10.1007/s40495-019-00170-z.

15. Lin, IY., Chiou, YS., Wu, LC., Tsai, CY., Chen, CT., Chuang, WC., Lee, MC., Lin, CC., Lin, TT., Chen, SC., Pan, MH, Ma, N*. CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-β, Wnt and STAT3 signaling pathways. Journal of Food and Drug Analysis. 2019. 27(1):184-194.

16. Lien, KW., Ling, MP., Pan, MH*, Assessing Japan Imported Food Products Radiation Doses and Exposure Risk Following the Fukushima Nuclear Accident. Exposure and Health. 2019. https://doi.org/10.1007/s12403-019-00306-y.

17. Lien, KW*, Chen, SY., Pan, MH, Ling, MP. Inspections of imported foods to Taiwan: an overview. Journal of Consumer Protection and Food Safety. 2019. https://doi.org/10.1007/s00003-018-1204-7.

18. Lien, KW., Wang, X., Pan, MH, Ling, MP*. Assessing Aflatoxin Exposure Risk from Peanuts and Peanut Products Imported to Taiwan. Toxins. 2019. 11(2) 80.

19. Wang, B*, Hui, Y., Liu, L., Zhao, A., Chiou, YS., Zhang, F., Pan, MH*. Optimized Extraction of Phenolics from Jujube Peel and Their Anti-inflammatory Effects in LPS-Stimulated Murine Macrophages. Journal of Agricultural and Food Chemistry. 2019. 67(6):1666-1673.

20. Wang, S., Pan, MH., Hung, WL., Tung, YC., Ho, CT. From white to beige adipocytes: therapeutic potential of dietary molecules against obesity and their molecular mechanisms. Food & Function. 2019. doi: 10.1039/c8fo02154f.

21. Lee, MJ*, Tsai, YJ., Lin, MY., You, HL., Kalyanam, N., Ho, CT., Pan, MH*. Calebin-A induced death of malignant peripheral nerve sheath tumor cells by activation of histone acetyltransferase. Phytomedicine. 2019. 3(57):377-384.

22. Yi, X., Zheng, Q., Pan, MH., Chiou, YS, Li, Z., Li, L., Chen, Y., Hu, J., Duan, S., Wei, S., Ding, B*. Liposomal vesicles-protein interaction: Influences of iron liposomes on emulsifying properties of whey protein. Food Hydrocolloids. 2019. 89:602-612.

23. Yi, X., Zheng, Q., Ding, B., Pan, MH., Chiou, YS, Li, L., Li, Z. Liposome-whey protein interactions and its relation to emulsifying properties. LWT - Food Science and Technology. 2019. 99 (2019):505-512.

24. Lee, PS., Teng, CY., Kalyanam N., Ho, CT., Pan, MH*. Garcinol reduces obesity in high-fat diet-fed mice by modulating composition of the gut microbiota. Molecular Nutrition and Food Research. 2019. 63(2):e1800390.

​​

2018​

1. Pan, MH*., Chen, JW., Kong, ZL., Wu, JC., Ho, CT., Lai, CS. Attenuation by Tetrahydrocurcumin of Adiposity and Hepatic Steatosis in Mice with High-Fat-Diet-Induced Obesity. Journal of Agricultural and Food Chemistry. 2018. 66 (48), pp 12685–12695.

2. Tung, YC., Chang, WT., Li, S., Wu, JC., Badmeav, V., Ho, CT., Pan, MH*. Citrus peel extracts attenuated obesity and modulated gut microbiota in mice with high-fat diet-induced obesity. Food & Function. 2018. 9; 3363-3373. 

3. Wang, X., Li, S., Wei, CC., Huang, J., Pan, MH., Shahidi, F., Ho, CT*. Anti-inflammatory effects of polymethoxyflavones from citrus peels: a review. Journal of Food Bioactives. 2018. 3:76-86.

4. Chen, PY., Ho, CT., Shahidi, F., Pan, MH*. Potential effects of natural dietary compounds on trimethylamine N-oxide (TMAO) formation and TMAO-induced atherosclerosis. Journal of Food Bioactives. 2018. 3:87-94.

5. Chiou, YS, Li, S, Ho, CT, Pan, MH*. Prevention of Breast Cancer by Natural Phytochemicals: Focusing on Molecular Targets and Combination Strategy. Molecular Nutrition & Food Research. 2018. doi: 10.1002/mnfr.201800392.

6. Chou, YC, Ho, CT, Pan, MH*. Immature Citrus reticulate Extract Promotes Browning of Beige Adipocyte in High Fat Diet-Induced C57BL/6 Mice. Journal of Agricultural and Food Chemistry. 2018. doi: 10.1021/acs.jafc.8b02719.

7. Bagal-Kestwal, DR, Pan, MH, Chiang, BH. Electrically nanowired-enzymes for probe modification and sensor fabrication. Biosensors and Bioelectronics. 2018. 121:223-235.

8. Wang, L, Pan, MH, Lo, CY, Zhao, H, Li, S, Ho, CT, Yang, G. Anti-fibrotic activity of polyphenol-enriched sugarcane extract in rats via inhibition of p38 and JNK phosphorylation. Food & Function. 2018. 21;9(2):951-958. doi: 10.1039/c7fo01617d.

9. Koh, YC, Pan, MH*. Review on Discovery and Development of Novel Phytochemicals Which can be Used in Functional Foods. Current Research in Nutrition and Food Science. 2018. 6(2).

10. Koh, YC, Yang, GL, Lai, CS, Weerawatnanakorn, M, Pan, MH*. Chemopreventive Effects of Phytochemicals and Medicines on M1/M2 Polarized Macrophage Role in Inflammation-Related Diseases. International Journal of Molecular Science. 2018. 19(8):2208.

11. Wu, JC, Tung, YC, Zheng, YN, Tsai, ML, Lai, CS, Ho, CT, Pan, MH*. 5-Demethylnobiletin is more effective than nobiletin in preventing AOM/DSS-induced colorectal carcinogenesis in ICR mice. Journal of Food Bioactives. 2018.

12. Chiou, YS, Zheng, YN, Tsai, ML, Lai, CS, Ho, CT, Pan, MH*. 5-Demethylnobiletin more potently inhibits colon cancer cell growth than nobiletin in vitro and in vivo. Journal of Food Bioactives. 2018.

13. Chiou, YS, Lee, PS, Pan, MH*. Food Bioactives and Their Effects on Obesity-Accelerated Inflammatory Bowel Disease. Journal of Agricultural and Food Chemistry. 2018. 31;66(4):773-779. doi: 10.1021/acs.jafc.7b05854.

14. Chou, YC, Ho, CT, Pan, MH*. Stilbenes: Chemistry and Molecular Mechanisms of Anti-obesity. Current Pharmacology Reports. 2018.

15. Pan, MH*, Wu, JC, Ho, CT, Lai, CS. Antiobesity molecular mechanisms of action: Resveratrol and pterostilbene. Biofactors. 2018. 44(1):50-60. doi: 10.1002/biof.1409.

16. Lee, PS, Chiou, YS, Ho, CT, Pan, MH*. Chemoprevention by resveratrol and pterostilbene: Targeting on epigenetic regulation. Biofactors. 2018. 44(1):26-35. doi: 10.1002/biof.1401.

17. Wu, JC, Tsai, ML, Lai, CS, Lo, CY, Ho, CT, Wang, YJ, Pan, MH*. Polymethoxyflavones precent benzo[a]pyrene/dextran sodium sulfate-induced colorectal carcinogenesis through modulating xenobiotic metabolism and ameliorate autophagic defect in ICR mice. International Journal of Cancer. 2018. 15; 142(8):1689-1701

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2017

1. Hung, WL, Yang, G, Wang, YC, Chiou, YS, Tung, YC, Yang MJ, Wang, BN, Ho, CT, Wang, Y, Pan, MH*. Protective effects of theasinensin A against carbon tetrachloride-induced liver injury in mice. Food & Function. 2017. 8(9):3276-3287.

2. Kimura, S, Tung, YC, Pan, MH, Su, NW, Lai, YJ, Cheng, KC. Black garlic: A critical review of its production, bioactivity, and application. Journal of Food and Drug Analysis. 2017. 25(1):62-70.

3. Tung, YC, Hsieh, PH, Pan, MH*, Ho, CT. Cellular models for the evaluation of the anti-obesity effect of selected phytochemicals from food and herbs. Journal of Food and Drug Analysis. 2017. 25(1): 100-110.

4. Wu, JC, Lai, CS, Tsai, ML, Ho, CT, Wang, YJ, Pan, MH*. Chemopreventive effect of natural dietary compounds on xenobiotic-induced toxicity. 2017. 25(1): 176-186.

5. Weerawatanakorn, M, Pan, MH. Phytochemical components of Carissa carandas and the inhibitory effects of fruit juice on inducible nitric oxide synthase and cyclooxygenase-2. Journal of Food Biochemistry. 2017. 41(3): e12343.

6. Lin, IY, Pan, MH, Lai, CS, Lin, TT, Chen, CT, Chung, TS, Chen, CL, Lin, CH, Chuang, WC, Lee, MC, Lin, CC, Ma, N. CCM111, the water extract of Antrodia cinnamomea, regulates immune-related activity through STAT3 and NF-κB pathways. Scientific Reports. 2017. 7(1):4862.

7. Lee, PS, Lee, CH, Pan, MH*. Cancer chemoprevetive effects of phytochemicals by suppressing cancer metastasis. Journal of Analytical & Pharmaceutical Research. 2017. 5(6): 00157.

8. Chen, RJ, Wu, PH, Ho, CT, Way, TD, Pan, MH, Chen, HM, Ho, YS, Wang, YJ. P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment. Cell Death and Disease. 2017. 8(8):e2985.

9. Pan, MH*, Yang, G, Li, S, Li, MY, Tsai, ML, Wu, JC, Badmaev, V, Ho, CT, Lai, CS. Combination of citrus polymethoxyflavones, green tea polyphenols and Lychee extracts suppresses obesity and hepatic steatosis in high-fat diet induced obese mice. Molecular Nutrition & Food Research. 2017. 61(11).

10. Pan, MH*, Wu, JC, Ho, CT, Badmaev, V. Effects of water extract of Curcuma longa (L.) roots on immunity and telomerase function. Journal of Complementary and Integrative Medicine. 2017. doi: 10.1515/jcim-2015-0107.

11. Chou, YC, Suh, JH, Wang, Y, Pahwa, M, Badmaev, V, Ho, CT, Pan, MH*. Boswellia serrata resin extract alleviates azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced colon tumorigenesis. Molecular Nutrition & Food Research. 2017. 61(9).

12. Pan, MH*. Introduction to the Special Issue: Dietary Natural Compounds. Journal of Food and Drug Analysis. 2017. 25(1): 1–2.

13. Chen, HP, Pan, MH, Chou, YY, Sung, C, Lee, KH, Leung, CM, Hsu, PC. Effects of di(2-ethylhexyl)phthalate exposure on 1,2-dimethyhydrazine-induced colon tumor promotion in rats. Food and Chemical Toxicology. 2017. 103: 157–167.

14. Tu, SH, Chiou, YS, Kalyanam, N, Ho, CT, Chen, LC, Pan, MH*. Garcinol sensitizes breast cancer cells to Taxol through the suppression of caspase-3/iPLA2 and NF-κB/Twist1 signaling pathways in a mouse 4T1 breast tumor model. Food & Function. 2017. 22;8(3):1067-1079.

15. Tang, W. Li, S, Liu, Y, Wu, JC, Pan, MH, Huang, MT, Ho, CT. Anti-diabetic activities of cis- and trans-2,3,5,4'-tetrahydroxystilbene 2-O-β-glucopyranoside from Polygonum multiflorum. Molecular Nutrition & Food Research. 2017. doi: 10.1002/mnfr.201600871.

16. Yang, GL, Li, Shiming, Yuan, Li, Yang, Yiwen, Pan, MH*. Effect of nobiletin on the MAPK/NF-κB signaling pathway in the synovial membrane of rats with arthritis induced by collagen. Food and Function. 2017. doi: 10.1039/c7fo01311f

17. Wang, SY, Wang, Y, Pan, MH , Ho, CT. Anti-obesity molecular mechanism of soy isoflavones: weaving the way to new therapeutic routes. Food and Function. 2017. doi: 10.1039/c7fo01094j

18. Lai, CS, Yang, GL, Li, SM, Lee, PS, Wang, BN, Chung, MC, Nagabhushanam, K, Ho, CT, Pan, MH*. 3’-Hydroxypterostilbene suppresses colitis-associated tumorigenesis by inhibition of IL-6/STAT3 signaling in mice. Journal of Agricultural and Food Chemistry. 2017. 65(44):9655-9664.

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2016

1. Lai, CS, Wu, JC, Ho, CT, Pan, MH*. Chemoprevention of obesity by dietary natural compounds targeting mitochondrial regulation. Molecular Nutrition & Food Research. 2016. 61(6). doi: 10.1002.

2. Pan, MH*, Tung, YC*, Yang, G, Li, S, Ho, CT. Molecular mechanisms of the anti-obesity effect of bioactive compounds in tea and coffee. Food & Function. 2016. 7(11): 4481-4491.

3. Tung, YC, Lin, YH, Chen, HJ, Chou, SC, Cheng, AC, Kalyanam, N, Ho, CT, Pan, MH*. Piceatannol exerts anti-obesity effects in C57BL/6 mice through modulating adipogenic proteins and gut microbiota. Molecules. 2016. 21(11): 1419.

4. Liou, WS, Lin, C, Lee, PS, Kalyanam, N, Ho, CT, Pan, MH*. Calebin-A induces cell cycle arrest in human colon cancer cells and xenografts in nude mice. Journal of Functional Foods. 2016. 26:781-791.

5. Chiou, YS, John, JA, Ho, CT, Pan, MH*, Shahidi, FS. Evaluation of chemopreventive effects in colitis-associated colon tumourigenesis and oral toxicity of the lipophilic epigallocatechin gallate-docosahexaenoic acid. Journal of Functional Foods. 2016. 24:48-56.

6. Wu, JC, Lai, CS, Lee, PS, Ho, CT, Liou, WS, Wang, YJ, Pan, MH*. Anti-cancer efficacy of dietary polyphenols is mediated through epigenetic modifications. Current Opinion in Food Science. 2016. 8:1-7.

7. Hung, WL, Hwang, LS, Shahidi, F, Pan, MH, Wang, Y, Ho, CT. Endogenous formation of trans fatty acids: Health implications and potential dietary intervention. Journal of Functional Foods. 2016. 25:14-24.

8. Wang, Y, Lee, PS, Chen, YF, Ho, CT and Pan, MH*. Suppression of Adipogenesis by 5-Hydroxy-3,6,7,8,3’,4’-Hexamethoxyflavone from Orange Peel in 3T3-L1 Cells. Journal of Medicinal Food. 2016. 19(9): 830-835.

9. Tsai, JH, Hsu, LS, Huang, HC, Lin, CL, Pan, MH, Hong HM and Chen WJ. 1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione induces G1 cell cycle arrest and autophagy in hela cervical cancer cells. International Journal of Molecular Sciences. 2016. 17(8):1274.

10. Chena, LC, Chen, MY, Tu, SH, Pan, MH, Lo, CY, Ho, CT, Wu, CH, Ho, YS. Pu-erh tea attenuates smoking-induced foam cell formation through inhibition of the α9-nicotinic-acetylcholine receptor expression in monocytes: An ex vivo study. Journal of Functional Foods. 2016. 22:132-144.

11. Lai, CS, Chen YY, Lee, PS, Kalyanam, N, Ho, CT, Liou, WS, Yu, RC, Pan, MH*. Bisdemethoxycurcumin Inhibits Adipogenesis in 3T3-L1 Preadipocytes and Suppresses Obesity in High-Fat Diet-Fed C57BL/6 Mice. Journal of Agricultural and Food Chemistry. 2016. 64 (4):821-830.

12. Zhen, J, Villani, TS, Guo, Y, Qi, Y, Chin, K, Pan, MH, Ho, CT, Simon, JE, Wu, Q. Phytochemistry, antioxidant capacity, total phenolic content and anti-inflammatory activity of Hibiscus sabdariffa leaves. Food Chemistry. 2016. 190:673-680.

13. Chiou, YS.; Huang, Q, Ho, CT, Wang, YJ, Pan, MH*. Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia. Free Radical Biology and Medicine. 2016. 94:1-16.

14. Chen, W, Jia, Z, Pan, MH, Babu, PV. A. Natural Products for the Prevention of Oxidative Stress-Related Diseases: Mechanisms and Strategies. Oxidative Medicine and Cellular Longevity. 2016.

15. Tu, SH.; Chen, MY, Chen, LC, Mao, YT, Ho, CH, Lee, WJ, Lin, YK, Pan, MH, Lo, CY, Chen, CL. Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study. Journal of Agricultural and Food Chemistry. 2016. 64 (16):3186-3195.

16. Tung, YC.; Li, S, Huang, Q, Hung, WL, Ho, CT, Wei, GJ, Pan, MH*. 5-Demethylnobiletin and 5-Acetoxy-6, 7, 8, 3’, 4’-pentamethoxyflavone Suppress Lipid Accumulation by Activating the LKB1-AMPK Pathway in 3T3-L1 Preadipocytes and High Fat Diet-Fed C57BL/6 Mice. Journal of Agricultural and Food Chemistry. 2016. 64 (16):3196-3205.

17. Pan, MH, Maresz, K, Lee, PS, Wu, JC, Ho, CT, Popko, J, Mehta, DS, Stohs, SJ, Badmaev, V. Inhibition of TNF-α, IL-1α, and IL-1β by Pretreatment of Human Monocyte-Derived Macrophages with Menaquinone-7 and Cell Activation with TLR Agonists In Vitro. Journal of Medicinal Food. 2016. 19(7):663-669.

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2015

1. Lai, CS., Liao, SN, Tsai, ML, Kalyanam, N, Majeed, M, Majeed, A, Ho, CT, Pan, MH.* Calebin-A inhibits adipogenesis and hepatic steatosis in high-fat diet-induced obesity via activation of AMPK signaling. Molecular Nutrition and Food Research. 2015. 59(10):1883-1895.

2. Wang, Y, Tsai, ML, Chiou, LY, Ho, CT, Pan, MH*. Antitumor Activity of Garcinol in Human Prostate Cancer Cells and Xenograft Mice. Journal of Agricultural and Food Chemistry. 2015. 63(41):9047-9052.

3. Hung, WL, Liu, CM, Lai, CS, Ho, CT, Pan, MH*. Inhibitory effect of garcinol against 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumorigenesis in mice. Journal of Functional Foods. 2015. 18:432-444.

4. Weerawatanakorn, M, Wu, JC, Pan, MH. Ho CT. Reactivity and stability of selected flavor compounds. Journal of Food and Drug Analysis , 2015. 23(2):176-190.

5. Ting, YW, Chiou, YS, Jiang, Y, Pan, MH, Lin, Z, Huang, Q. Safety evaluation of tangeretin and the effect of using emulsion-based delivery system: Oral acute and 28-day sub-acute toxicity study using mice. Food Research International. 2015. 74:140-150.

6. Tung, YC, Tsai, ML, Kuo, FL, Lai, CS, Badmaev, V, Ho, CT, Pan, MH*. Se-Methyl-L-selenocysteine Induces Apoptosis via Endoplasmic Reticulum Stress and the Death Receptor Pathway in Human Colon Adenocarcinoma COLO 205 Cells. Journal of Agricultural and Food Chemistry. 2015. 63(20):5008-5016.

7. Weerawatanakorn, M, Lee, YL, Tsai, CY, Lai, CS, Wan, X, Ho, CT, Li, S, Pan, MH*. Protective effect of theaflavin-enriched black tea extracts against dimethylnitrosamine-induced liver fibrosis in rats. Food & Function. 2015. 6: 1832-1840.

8. Bai N, He K, Roller M, Lai CS, Bai L, Pan, MH*. Flavonolignans and other constituents from Lepidium meyenii with activities in anti-inflammation and human cancer cell lines. Journal of Agricultural and Food Chemistry. 2015. 63(9):2458-2463.

9. Hsu, PC, Kuo, YT, Leon, Guo Y, Chen, JR, Tsai, SS, Chao, HR, Teng, YN, Pan, MH*. The adverse effects of low-dose exposure to Di(2-ethylhexyl) phthalate during adolescence on sperm function in adult rats. Environmental Toxicology. 2014. 31(6):706-712.

10. Pan, MH*, Chiou, YS, Chen, LH, Ho, CT. Breast cancer chemoprevention by dietary natural phenolic compounds: specific epigenetic related molecular targets. Molecular Nutrition and Food Research. 2015. 59(1):21-35.

11. Huang, CY, Hsieh, NT, Pan, MH, Li, CI, Chou, YH, Chiou, YS, Lee MF. Resveratrol and pterostilbene regulate MED28 (magicin/EG1) expression and cell growth in MCF7 human breast cancer cells. Journal of Functional Foods. 2015. 12:158–167.

12. Ting, Y, Chiou, YS, Pan, MH, Ho, CT, Huang, Q. In vitro and in vivo anti-cancer activity of tangeretin against colorectal cancer was enhanced by emulsion-based delivery system. Journal of Functional Foods. 2015. 15:267-273.

13. Badmaev, V, Hatakeyama, Y, Yamazaki, N, Noro, A, Mohamed, F, Ho, CT, Pan, MH*. Preclinical and clinical effects of Coleus forskohlii, Salacia reticulata and Sesamum indicum modifying pancreatic lipase inhibition in vitro and reducing total body fat. Journal of Functional Foods. 2015. 15:44-51.

14. Ravishankar, B, Dound, YA, Mehta, DS, Ashok, BK, Souza, A, Pan, MH*, Ho CT, Badmaev V, Vaidya ADB. Safety assessment of menaquinone-7 for use in human nutrition. Journal of Food and Drug Analysis. 2015. 23:99-108.

15. Lai, CS, Wu, JC, Pan, MH*. Molecular mechanism on functional food bioactives for anti-obesity. Current Opinion in Food Science. 2015. 2:9-13.

16. Lee MF, Lai CS, Cheng AC, Hou JS, Badmaevd V, Ho CT, Pan MH*. Krill oil and xanthigen separately inhibit high fat diet induced obesity and hepatic triacylglycerol accumulation in mice. Journal of Functional Foods. 2015. 19:913-921.

17. Janporna S, Ho CT, Chavasitc V, Pan MH, Chittrakorna S, Ruttarattanamongkola K, Weerawatanakorn M. Physicochemical properties of Terminalia catappa seed oil as a novel dietary lipid source. Journal of Food and Drug Analysis, 2015. 23(2):201-209.

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2014

1. Cheng TC, Lai CS, Chung MC, Kalyanam N, Majeed M, Ho CT, Ho YS, Pan MH*. Potent Anti-Cancer Effect of 3'-Hydroxypterostilbene in Human Colon Xenograft Tumors. PLoS One. 2014. 9(11):1-8.

2. Hung WL, Tsai ML, Sun PP, Tsai CY, Yang CC, Ho CT, Cheng AC, Pan MH*. Protective effects of garcinol on dimethylnitrosamine-induced liver fibrosis in rats. Food & Function. 2014. 5:2883–2891.

3. Ma N, Lai CS, Chung CH, Yang JM, Hsu KC, Chen CY, Chung TS, Li S, Ho CT, Pan MH*. 5-Demethyltangeretin is more potent than tangeretin in inhibiting dimethylbenz(a)anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin tumorigenesis. Journal of Functional Foods. 2014. 11:528-537.

4. Tsai ML, Chiou YS, Chiou LY, Ho CT, Pan MH*. Garcinol suppresses inflammation -associated colon carcinogenesis in mice. Molecular Nutrition and Food Research. 2014. 58(9):1820-1829.

5. Chiou YS, Wu JC, Huang Q, Shahidi F, Wang Y J, Ho CT, Pan MH*. Metabolic and colonic microbiota transformation may enhance the bioactivities of dietary polyphenols. Journal of Functional Foods. 2014 7:3-25.

6. Weerawatanakorn M, Hsieh SC, Tsai ML, Lai CS,Wu LM, Badmaev V, Ho CT, Pan MH*. Inhibitory effect of tetrahydrocurcumin on dimethylnitrosamine-induced liver fibrosis in rats. Journal of Functional Foods. 2014. 7:305-313.

7. Weerawatanakorn M, Yang JR, Tsai ML, Lai CS, Ho CT, Pan MH*. Inhibitory effects of Momordica grosvenori Swingle extracts on 12-Otetradecanoylphorbol-13-acetate-induced skin inflammation and tumor promotion in mouse skin. Food & Function. 2014. 5(2):257-264.

8. Pan MH*, Lai CS, Tsai ML, Ho CT. Chemoprevention of nonalcoholic fatty liver disease by dietary natural compounds. Molecular Nutrition and Food Research. 2014. 58(1):147-171.

9. Wu JC, Tsai ML, Lai CS, Wang YJ, Ho CT, Pan MH*. Chemopreventative effects of tetrahydrocurcumin on human diseases. Food & Function. 2014. 5(1):12-17.

10. Chu HF, Pan MH, Ho CT, Tseng YH, Wang WW, Chau CF. Variations in the Efficacy of Resistant Maltodextrin on Body Fat Reduction in Rats Fed Different High-Fat Models. Journal of Agricultural and Food Chemistry, 2014. 62(1),192-197.

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2013

1. Wang CH, Lin JH, Lu TJ, Chiang AN, Chiou ST, Chen YA, Pan MH, Hsieh SC. Establishment of reporter platforms capable of detecting NFkappaB mediated immuno-modulatory activity. Journal of Agricultural and Food Chemistry. 2013. 1(51):12582-12587.

2. Hsu CH, Ho YS, Lai CS, Hsieh SC, Chen LH, Lin E, Ho CT, Pan MH*. Hexahydro-b-acids potently inhibit 12-O-tetradecanoylphorbol 13-acetateinduced skin inflammation and tumor promotion in mice. Journal of Agricultural and Food Chemistry. 2013. 61(47):11541-11549.

3. Tsai JH, Hsu LS, Lin CL, Hong HM, Pan MH, Way TD, Chen WJ. 3,5,4'-Trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast cancer cell invasiveness by downregulation of PI3K/Akt and Wnt/b-catenin signaling cascades and reversal of epithelial-mesenchymal transition. Toxicology and Applied Pharmacology. 2013. 272(3):746-756.

4. Coppin J, Xu Y, Chen H, Pan MH, Ho CT, Juliani R, Simon JE, Wu Q. Determination of flavonoids by LC/MS and anti-inflammatory activity in Moringa oleifera. Journal of Functional Foods. 2013. 5 (4):1892-1899.

5. Lai CS, Ho MH, Tsai ML, Li S, Badmaev V, Ho CT, Pan MH*. Suppression of adipogenesis and obesity in high-fat induced mouse model by hydroxylated polymethoxyflavones. Journal of Agricultural and Food Chemistry. 2013. 61(43):10320-10328.

6. Ting Y, Li CC, Pan MH, Ho CT, Huang Q. Effect of a labile methyl donor on the transformation of 5-demethyltangeretin and the related implication on bioactivity. Journal of Agricultural and Food Chemistry. 2013. 61(34):8090-8097.

7. Tseng LH, Hsu PC, Lee CW, Tsai SS, Pan MH, Li MH. Developmental exposure to decabrominated diphenyl ether (BDE-209): effects on sperm oxidative stress and chromatin DNA damage in mouse offspring. Environmental Toxicology. 2013. 28(7):380-389.

8. Chiou YS, Sang S, Cheng KH, Ho CT, Wang YJ, Pan MH*. Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1- dependent signaling pathway in CD34+ skin stem cells and skin tumors . Carcinogenesis. 2013. 34(6):1315-1322.

9. Lai CS, Li S, Miyauchi Y, Suzawa M, Ho CT, Pan MH*. Potent anticancer effects of citrus peel flavonoids in human prostate xenograft tumors. Food & Function. 2013. 4(6):944-9.

10. Lee MF, Liu ML, Cheng AC, Tsai ML, Ho CT, Liou WS, Pan MH*. Pterostilbene inhibits dimethylnitrosamine-induced liver fibrosis in rats . Food Chemistry. 2013. 138(2-3):802-807.

11. Huang CS, Ho CT, Tu SH, Pan MH, Chuang CH, Chang HW, Chang CH, Wu CH, Ho YS. Long-term ethanol exposure-induced hepatocellular carcinoma cell migration and invasion through lysyl oxidase activation are attenuated by combined treatment with pterostilbene and curcumin analogues. Journal of Agricultural and Food Chemistry. 2013. 61(18):4326-4335.

12. Lai CS, Li S, Liu CB, Miyauchi Y, Suzawa M, Ho CT, Pan MH*. Effective suppression of azoxymethane-induced aberrant crypt foci formation in mice with citrus peel flavonoids. Molecular Nutrition and Food Research. 2013. 57(3):551-555.

13. Pan MH*, Lai CS, Wang H, Lo CY, Ho CT, Li S. Black tea in chemoprevention of cancer and other human diseases. Food Science and Human Wellness. 2013. 2(1):12-21.

14. Lee MF, Tsai ML, Sun PP, Chien LL, Cheng AC, Ma NJ, Ho CT, Pan MH*. Phyto-power dietary supplement potently inhibits dimethylnitrosamine induced liver fibrosis in rats. Food & Function. 2013. 4(3):470-475.

15. Li S, Lo CY, Pan MH, Lai CS, Ho CT. Black tea: chemical analysis and stability. Food & Function. 2013. 4(1):10-18.

16. Pan MH*, Lai CS, Wu JC, Ho CT. Epigenetic and disease targets by polyphenols. Current Pharmaceutical Design. 2013. 19(34):6156-6185.

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2012

1. Pan MH*, Li S, Lai CS, Miyauchi Y, Suzawa M, Ho CT. Inhibitory effect of citrus flavonoids on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice. Food Science and Human Wellness. 2012. 1(1):65-73.

2. Chen RJ, Tsai SJ, Ho CT, Pan MH, Ho YS, Wu CH, Wang YJ. Chemopreventive effects of pterostilbene on urethane-induced lung carcinogenesis in mice via the inhibition of EGFR-mediated pathways and the induction of apoptosis and autophagy. Journal of Agricultural and Food Chemistry. 2012. 60(46):11533-11541.

3. Tsai ML, Lai CS, Chang YH, Chen WJ, Ho CT, Pan MH*. Pterostilbene, a natural analogue of resveratrol, potently inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/ 12-O-tetradecanoylphorbol -13-acetate (TPA)-induced mouse skin carcinogenesis. Food & Function. 2012. 3(11):1185-1194.

4. Chang LH, Huang HS, Wu PT, Jou IM, Pan MH, Chang WC, Wang DD, Wang JM. Role of Macrophage CCAAT/Enhancer Binding Protein Delta in the Pathogenesis of Rheumatoid Arthritis in Collagen-Induced Arthritic Mice. PLoS One. 2012. 7(9):1-14.

5. Zhong Y, Chiou YS, Pan MH, Shahidi F. Anti- inflammatory activity of lipophilic epigallocatechin gallate (EGCG) derivatives in LPS-stimulated murine macrophages. Food Chemistry. 2012. 134(2):742-748.

6. Kuo YC, Lai CS, Tsai CY, Nagabhushanam K, Ho CT, Pan MH*. Inotilone suppresses phorbol ester–induced inflammation and tumor promotion in mouse skin. Molecular Nutrition and Food Research. 2012. 56(8):1324-1332.

7. Lin VC, Tsai YC, Lin JN, Fan LL, Pan MH, Ho CT, Wu JY, Way TD. Activation of AMPK by pterostilbene suppresses lipogenesis and cell cycleprogression in p53 positive and negative human prostate cancer cells. Journal of Agricultural and Food Chemistry. 2012. 60(25):6399-6407.

8. Chiou YS, Ma NJ, Sang S, Ho CT, Wang YJ, Pan MH*. Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice. Journal of Agricultural and Food Chemistry. 2012. 60(13):3441-3451.

9. Lai CS, Tsai ML, Badmaev V, Jimenez M, Ho CT, Pan MH*. Xanthigen suppresses preadipocyte differentiation and adipogenesis through down-regulation of PPARr and C/EBPs, and modulation of SIRT-1, AMPK and FOXO pathways. Journal of Agricultural and Food Chemistry. 2012. 60(4):1094-1101.

10. Ou JL, Tu CC, Hsu PI, Pan MH, Lee CC, Tsay FW, Wang HM, Cheng LC, Lai KH, Yu HC. Prevalence and risk factors of erosive esophagitis in Taiwan. Journal of the Chinese Medical Association. 2012. 75(2):60-64.

11. Hsieh WJ, Chiou ST, Pan MH, Hsieh SC. Establishment and Evaluation of Biotechnological Platform for Screening Health Food with Antiinflammation Ability. Journal of Traditional and Complementary Medicine. 2012. 2(1):76-80.

12. Pan MH*, Lai CS, Tsai ML, Wu JC, Ho CT. Molecular mechanisms for anti-aging by natural dietary compounds. Molecular Nutrition and Food Research. 2012. 56(1):88-115.

13. Zhong Y, Chiou YS, Pan MH, Ho CT, Shahidi F. Protective effects of epigallocatechin gallate (EGCG) derivatives on azoxymethane-induced colonic carcinogenesis in mice. Journal of Functional Foods. 2012. 4(1):323-330.

14. Ho, CT, Pan MH, Lai, CS, Li, S. Polymethoxyflavones as food factors for the management of inflammatory diseases. Journal of Food and Drug Analysis. 2012. 20:337-341.

15. Kuo, JM, Yang, JI, Chen, WM, MH Pan, Tsai, ML, Lai YJ, Hwang, A, Pan BS, Lin CY. Purification and characterization of a thermostable keratinase from Meiothermus sp. I40. International Biodeterioration and Biodegradation. 2012. 70:111-116.

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2011

1. Lai, CS, Wu, JC, Yu, SF, Badmaev, V, Nagabhushanam, K, Ho, CT, Pan MH*. Tetrahydrocurcumin is more effective than curcumin in preventing azoxymethane-induced colon carcinogenesis. Molecular Nutrition and Food Research. 2011. 55(12):1819-1828.

2. Lai CS, Pan MH. Mechanism for Possible Chemopreventive Effects of Natural Dietary Compounds on Smoking-induced Tumorigenesis. Journal of Experimental & Clinical Medicine. 2011. 3(6):262-271.

3. Wu, JC, Lai, CS, Badmaev, V, Nagabhushanam, K, Ho, CT, Pan MH*. Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells. Molecular Nutrition and Food Research. 2011. 55(11):1646-1654.

4. Pan MH*, Chiou, YS, Tsai ML, Ho CT. Anti-inflammatory activity of traditional Chinese medicinal herbs. Journal of Traditional and Complementary Medicine. 2011. 1(1):8-24.

5. Qiu P, Guan H, Dong P, Guo S, Zheng J, Li S, Chen Y, Ho CT, Pan MH, McClements DJ, Xiao H. The inhibitory effects of 5-hydroxy- 3,6,7,8,3',4'-hexamethoxyflavone on human colon cancer cells. Molecular Nutrition and Food Research. 2011. 55(10):1523-1532.

6. Shen D, Pan MH, Wu QL, Park CH, Juliani HR, Ho CT, Simon JE. A Rapid LC/MS/MS Method for the Analysis of Nonvolatile Antiinflammatory Agents from Mentha spp. Journal of Food Science. 2011. 76(6):900-908.

7. Kuo DH, Tsai SW, Pan MH*. Magnolol blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries. Food Chemistry. 2011. 127:135- 140.

8. Lai CS, Lai YS, Kuo DH, Wu CH, Ho CT, Pan MH*. Magnolol potently suppressed lipopolysaccharide-induced iNOS and COX-2 expression via downregulating MAPK and NF-kB signaling pathways. Journal of Functional Foods. 2011. 3(3):198-206.

9. Kong ZL, Yu SC, Dai SA, Tu CC, Pan MH, Liu YC. Polyoxygenated Sterols from Freshwater Clam. Helvetica Chimica Acta, 2011, 94(5):892-896.

10. Pan MH*, Hong HM, Lin CL, Jhang AZ, Tsai JH, Badmaev V, Nagabhushanam K, Ho CT, Chen WJ. Se-methylselenocysteine inhibits lipopolysaccharide-induced NF-κB activation and iNOS induction in RAW 264.7 murine macrophages. Molecular Nutrition and Food Research. 2011. 55(5):723-32.

11. Tang W, Chen LH, Daun H, Ho CT, Pan MH*. Inhibitory effects of hexahydro-bata-acids in LPS-stimulated murine macrophage. Journal of Functional Foods. 2011. 3:215-222.

12. Yen JH, Weng CY, Li S, Lo YH, Pan MH, Fu SH, Ho CT, Wu MJ. Citrus flavonoid, 5-demethylnobiletin, suppresses scavenger receptor expression in THP-1 cells and alters lipid homeostasis in HepG2 liver cells. Molecular Nutrition and Food Research. 2011. 55(5):733-748.

13. Liu CB, Chen LH, Cheng AC, Chen WJ, Tsai ML, Liu Y, Ho CT, Pan MH*. Hexahydro-b-acids induce apoptosis through mitochondrial pathway, GADD153 expression, and caspase activation in human leukemia cells. Food and Chemical Toxicology. 2011. 49(4):1033-1042.

14. Qiu P, Guan H, Dong P, Li S, Ho CT, Pan MH, McClements DJ, Xiao H. The p53, Bax, and p21-dependent inhibition of colon cancer cell growth by 5-hydroxy polymethoxyflavones. Molecular Nutrition and Food Research. 2011. 55(4):613-622.

15. Bai N, He K, Roller M, Lai CS, Shao X, Pan MH, Bily A, Ho CT. Flavonoid glycosides from Microtea debilis and their cytotoxic and anti-inflammatory effects. Fitoterapia. 2011. 82(2):168-172.

16. Tu SH, Ku CY, Ho CT, Chen CS, Huang CS, Lee CH, Chen LC, Pan MH, Chang HW, Chang CH, Chang YJ, Wei PL, Wu CH, Ho YS. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced a9-nicotinic acetylcholine receptor upregulation in human breast cancer cells. Molecular Nutrition and Food Research. 2011. 55(3):455-466.

17. Cheng AC, Lee MF, Tsai ML, Lai CS, Lee JH, Ho CT, Pan MH*. Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells. Food and Chemical Toxicology. 2011. 49(2):485-493.

18. Chiou YS, Tsai ML, Nagabhushanam K, Wang YJ, Wu CH, Ho CT, Pan MH*. Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2- related factor 2 (Nrf2)-mediated antioxidant signaling pathway. Journal of Agricultural and Food Chemistry. 2011. 59(6):2725-2733.

19. Lai CS, Tsai ML, Cheng AC, Li S, Lo CY, Wang Y, Xiao H, Ho CT, Wang YJ, Pan MH*. Chemoprevention of colonic tumorigenesis by dietary hydroxylated polymethoxyflavones in azoxymethane-treated mice. Molecular Nutrition and Food Research. 2011. 55(2):278-290.

20. Pan MH*, Chiou YS, Wang YJ, Ho CT, Lin JK. Multistage carcinogenesis process as molecular targets in cancer chemoprevention by epicatechin-3-gallate. Food & Function. 2011. 2(2):101-110.

21. Pan MH*, Lin YT, Lin CL, Wei CS, Ho CT, Chen WJ. Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation. Evidence-Based Complementary and Alternative Medicine. 2011. 2011:1-12.

22. Chen CS, Lee CH, Hsieh CD, Ho CT, Pan MH, Huang CS, Tu SH, Wang YJ, Chen LC, Chang YJ, Wei PL, Yang YY, Wu CH, Ho YS. Nicotineinduced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins. Breast Cancer Research and Treatment. 2011. 125(1):73-87.

23. Pan MH*, Lai CS, Wu JC, Ho CT. Molecular mechanisms for chemoprevention of colorectal cancer by natural dietary compounds. Molecular Nutrition and Food Research. 2011. 55(1):32-45.

24. Lee MF, Pan MH, Chiou YS, Cheng AC, Huang H. Resveratrol modulates MED28 (magicin/EG-1) expression and inhibits epidermal growth factor (EGF)-induced migration in MDA-MB-231 human breast cancer cells. Journal of Agricultural and Food Chemistry. 2011. 59(21):11853-11861.